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AutoGendefinition and how it works in 2026

AutoGen
Microsoft's open-source framework for multi-agent conversation โ€” agents talk to each other to solve problems collaboratively, with explicit support for code execution and human-in-the-loop.

AutoGen was Microsoft Research's contribution to the multi-agent space. The core pattern: define agents (each with its own system prompt and tools), let them converse, intervene when needed. The "conversation" metaphor is the differentiator โ€” agents literally talk to each other in natural language until they reach a conclusion.

Strengths: explicit human-in-the-loop support, strong code execution, research-grade flexibility. Used heavily in academic AI research. Weaknesses: conversation can be inefficient; agents can over-talk; less production polish than LangGraph or CrewAI.

In 2026, AutoGen is most popular in research contexts and at Microsoft-aligned enterprises. For most production work, LangGraph or vendor SDKs are the better choice. AutoGen-Studio (a GUI on top) makes it more accessible.

Frequently asked

AutoGen vs CrewAI?+

AutoGen for research and conversational multi-agent. CrewAI for role-based crews. Both are open source, both work โ€” pick by which mental model fits your problem.

Is AutoGen still maintained?+

Yes, by Microsoft Research. AutoGen 0.4 was a major rewrite. Production users should expect occasional API changes; pin versions for stability.

Related terms

What is AutoGen? ยท Glossary ยท AI Agent Rank